Thoracoscopic Resection of a Nonseminomatous Primary Mediastinal Germ Cell Tumor

Semin Thorac Cardiovasc Surg. 2019 Winter;31(4):870-872. doi: 10.1053/j.semtcvs.2019.04.004. Epub 2019 Apr 11.


PMNGCT is an independent predictor of poor prognosis despite advances in multidisciplinary management. Multidrug chemotherapy followed by aggressive surgical resection remains the mainstay of treatment. Although associated with significant morbidity, an open surgical approach is traditionally used. We describe the first reported case, to our knowledge, of a patient who underwent resection of a PMNGCT via a minimally invasive approach following induction chemotherapy.

Keywords: Germ cell tumor; PMNGCT; Thoracoscopic surgery.

Publication types

  • Video-Audio Media

MeSH terms

  • Adult
  • Chemotherapy, Adjuvant
  • Humans
  • Male
  • Mediastinal Neoplasms / diagnostic imaging
  • Mediastinal Neoplasms / pathology
  • Mediastinal Neoplasms / surgery*
  • Neoadjuvant Therapy
  • Neoplasms, Germ Cell and Embryonal / diagnostic imaging
  • Neoplasms, Germ Cell and Embryonal / pathology
  • Neoplasms, Germ Cell and Embryonal / surgery*
  • Testicular Neoplasms / diagnostic imaging
  • Testicular Neoplasms / pathology
  • Testicular Neoplasms / surgery*
  • Thoracic Surgery, Video-Assisted*
  • Treatment Outcome

Supplementary concepts

  • Nonseminomatous germ cell tumor