Objective: To explore serum levels of measles and rubella IgG antibodies among mothers and infants. Methods: According to the inclusion and exclusion criteria, we selected 319 puerperae and their infants in maternal hospitals of Songjiang district November 2016 to February 2017, venous blood were collected and serum measles and rubella IgG antibodies were measured using ELISA. To study the correlation between the level of measles and rubella antibodies in infants and mothers' by using the Spearman's correlation analysis. Results: The age at delivery was (29.71±4.25) years old; and the gestational age at delivery was (39.06±1.30) weeks. The positive rate and protection rate of measles antibody in puerperae were 82.5% (243/319) and 43.3% (135/319), the GMC [M (QR)] was 655.74 (251.21-1 299.02) mIU/ml. The positive rate of rubella antibody in puerperae was 61.1% (195/319), the GMC [M (QR)] was 31.34 (11.65-73.61) IU/ml. The positive rate and protection rate of measles antibody in infants were 84.1% (270/321) and 46.1% (148/321), the GMC [M (QR)] was 665.07 (279.63-1 544.07) mIU/ml. The positive rate of rubella antibody in infants was 69.5% (223/321), the GMC [M (QR)] was 40.30 (16.12-98.48) IU/ml. There was statistical difference in measles (Z=-14.64, P<0.001) and rubella (Z=-8.66, P<0.001) antibody levels between mothers and infants. There was positive correlation in measles (r=0.76, P<0.001) and rubella (r=0.86, P<0.001) antibody level between mothers and infants. Conclusion: The maternal antibody of measles and rubella had a concentration effect. The level of measles and rubella antibodies in the infants was higher than that in the mothers' and increased with the increase of the level of measles and rubella antibodies in the mothers.
目的： 了解上海市松江区产妇及新出生婴儿麻疹和风疹的抗体水平。 方法： 于2016年11月至2017年2月，以松江区妇幼保健院符合纳入排除标准的319名产妇及其新生儿作为研究对象，采用ELISA检测研究对象血清的麻疹和风疹IgG抗体几何平均浓度（GMC），比较产妇和婴儿间风疹和麻疹抗体水平差异，采用Spearman相关分析研究产妇与婴儿间麻疹和风疹抗体水平的相关性。 结果： 产妇分娩年龄为（29.71±4.25）岁，分娩时胎儿的胎龄为（39.06±1.30）周；麻疹抗体阳性率为82.5%（243/319），抗体保护率为43.3%（135/319），抗体GMC的M（QR）值为655.74（251.21~1 299.02）mIU/ml；风疹抗体阳性率为61.1%（195/319），抗体GMC的M（QR）值为31.34（11.65~73.61）IU/ml。新生儿麻疹抗体阳性率为84.1%（270/321），抗体保护率为46.1%（148/321），GMC的M（QR）值为665.07（279.63~1 544.07）mIU/ml；风疹抗体阳性率为69.5%（223/321），GMC的M（QR）值为40.30（16.12~98.48）IU/ml。产妇及婴儿间麻疹（Z=-14.64，P<0.001）、风疹（Z=-8.66，P<0.001）抗体GMC差异有统计学意义。产妇及婴儿间麻疹（r=0.76，P<0.001）、风疹（r=0.86，P<0.001）抗体水平存在正相关关系。 结论： 母传麻疹和风疹抗体存在浓缩效应，新生儿麻疹和风疹抗体水平高于母亲，且随着母亲抗体水平的升高而升高。.
Keywords: Antibody; Measles; Mothers and infants; Rubella.