A therapeutic effect of cbd-enriched ointment in inflammatory skin diseases and cutaneous scars

Clin Ter. Mar-Apr 2019;170(2):e93-e99. doi: 10.7417/CT.2019.2116.

Abstract

Objective: To investigate the therapeutic effect of CBD-ointment administered on severe skin chronic diseases and/or on their outcome scars.

Methods: A spontaneous, anecdotal, retrospective study of 20 patients with two most frequent skin disorders: psoriasis (n: 5 patients), atopic dermatitis (n: 5) and resulting outcome scars (n: 10). The subjects were instructed to administer topical CBD-enriched ointment to lesioned skin areas twice daily for three months treatment.

Results: Based on skin evaluations (hydration, TEWL, elasticity), clinical questionnaires (SCORAD, ADI, PASI), and supported by photographic data and investigators' clinical assessment, the results showed that topical treatment with CBD-enriched ointment significantly improved the skin parameters, the symptoms and also the PASI index score. No irritant or allergic reactions were documented during the period treatment.

Conclusions: The topical administration of CBD ointment, without any THC, is a safe and effective non-invasive alternative for improve the quality of life in patients with some skin disorders, especially on inflammatory background.

Keywords: CBD; Ointment; Quality of life; Skin.

MeSH terms

  • Administration, Topical
  • Adult
  • Aged
  • Aged, 80 and over
  • Cannabidiol / administration & dosage*
  • Cicatrix / drug therapy*
  • Dermatitis, Atopic / drug therapy*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Ointments
  • Psoriasis / drug therapy*
  • Quality of Life
  • Retrospective Studies
  • Skin / pathology
  • Treatment Outcome
  • Young Adult

Substances

  • Ointments
  • Cannabidiol