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. 2019 Aug 1;58(15):2167-2171.
doi: 10.2169/internalmedicine.2298-18. Epub 2019 Apr 17.

Endoscopic Features and Diagnostic Procedures of Eosinophilic Gastroenteritis

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Free PMC article

Endoscopic Features and Diagnostic Procedures of Eosinophilic Gastroenteritis

Keigo Ashitani et al. Intern Med. .
Free PMC article

Abstract

No specific endoscopic features for eosinophilic gastroenteritis (EGE) have been reported previously. This study therefore evaluated the endoscopic findings of six patients with EGE. The diagnosis was confirmed based on gastrointestinal symptoms, pathological findings on biopsy, and the absence of other diseases. The site of the lesion was identified based on eosinophilic infiltration with ≥20 cells per high-power field during a pathological specimen analysis. Flattening of the small intestinal villi was observed in four patients; we speculate that this may be a specific feature in the diagnosis of EGE.

Keywords: endoscopy; eosinophilic gastroenteritis; eosinophils; esophagus; gastroenteritis; intestines.

Conflict of interest statement

The authors state that they have no Conflict of Interest (COI).

Figures

Figure 1.
Figure 1.
Esophagogastroduodenoscopy demonstrating shortening and flattening of villi in the overall biopsy specimen of the duodenum in one case. Eosinophil infiltration was also observed in this patient.
Figure 2.
Figure 2.
(a, b) Colonoscopy showing mucosal edema and erythema in the terminal ileum. In four of six patients, flattening of the villi was observed in the overall biopsy specimens.
Figure 3.
Figure 3.
Oral double-balloon endoscopy showing flattening of the villi in the overall biopsy specimen of the jejunum.

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