Use of low dose of rFVIIa (recombinant Factor VII activated) to control late bleeding after percutaneous dilational tracheostomy

Dario Nicosia; Antonino Federico; Ivan Vigna; Pasquale Iozzo; Giovanni Misseri; Andrea Cortegiani

doi:10.1002/ccr3.2061

Use of low dose of rFVIIa (recombinant Factor VII activated) to control late bleeding after percutaneous dilational tracheostomy

Clin Case Rep. 2019 Feb 19;7(4):665-667. doi: 10.1002/ccr3.2061. eCollection 2019 Apr.

Authors

Dario Nicosia¹, Antonino Federico¹, Ivan Vigna¹, Pasquale Iozzo¹, Giovanni Misseri¹, Andrea Cortegiani¹

Affiliation

¹ Department of Surgical, Oncological and Oral Science (Di.Chir.On.S.), Section of Anesthesia, Analgesia, Intensive Care and Emergency, Policlinico Paolo Giaccone University of Palermo Palermo Italy.

Abstract

In our case, the use of a low intravenous bolus dose of rFVIIa (recombinant factor VII activated; 15-20 mcg/kg) was effective and uneventful in controlling late postprocedural PDT bleeding associated with thrombocytopenia that cannot be corrected and after all other treatments failed.

Keywords: Thrombocytopenia; activated factor VII; percutaneous tracheostomy; postoperatory bleeding; rFVIIa.

Publication types

Case Reports