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Editorial
. 2019 Feb 27;6(1):e000890.
doi: 10.1136/openhrt-2018-000890. eCollection 2019.

Association of moderately elevated trimethylamine N-oxide with cardiovascular risk: is TMAO serving as a marker for hepatic insulin resistance

James J DiNicolantonio  1 , Mark McCarty  2 , James OKeefe  3
Affiliations
Editorial

Association of moderately elevated trimethylamine N-oxide with cardiovascular risk: is TMAO serving as a marker for hepatic insulin resistance

James J DiNicolantonio et al. Open Heart. .
No abstract available

Keywords: atherosclerosis; carnitine; choline; omega-3; trimethylamine-N-oxide.

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Conflict of interest statement

Competing interests: JJD is the author of The Salt Fix and Superfuel. MM: owner and science director of NutriGuard Research, a nutraceutical company which, among other things, sells berberine and astaxanthin supplements. JO: chief medical officer and founder of CardioTabs, a nutraceutical company which sells omega-3 supplements, and has a major ownership interest in the company.

Figures

Figure 1
Figure 1
Measures which increase adiponectin, increase GLP-1 activity, control metabolic syndrome and activate hepatic AMPK or PPARalpha may decrease elevated TMAO and associated vascular/metabolic risk. GLP-1, glucagon-like peptide-1; TMAO, trimethylamine-N-oxid.
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