Long-Term Anatomic and Visual Outcome Following Vitrectomy for Stage 4B and 5 Retinopathy of Prematurity

Ophthalmic Surg Lasers Imaging Retina. 2019 Apr 1;50(4):208-214. doi: 10.3928/23258160-20190401-02.


Background and objectives: Surgical indications in stages 4B and 5 retinopathy of prematurity (ROP) are not universally accepted. The authors' purpose is to evaluate the long-term anatomic and visual outcomes of vitrectomy for retinal detachment (RD) associated with stages 4B and 5 ROP.

Patients and methods: Data of patients who consecutively underwent vitrectomy for stages 4B and 5 ROP from 1999 to 2013 were retrospectively reviewed and included grade of retinal attachment and visual acuity (VA) at the last follow-up.

Results: Seventy eyes of 38 infants were included: 23 with stage 4B and 47 with stage 5 ROP. Lens-sparing vitrectomy was performed in 11 eyes, combined lensectomy / vitrectomy in 59 eyes. Mean follow-up was 8.5 years. Anatomic success was maintained in 41 eyes (58.5%), and among them, VA greater than 5/200 was achieved in 17 eyes (41.4%).

Conclusion: The long-term visual and anatomic success rates were encouraging for the surgical correction of RD associated with late stages ROP. [Ophthalmic Surg Lasers Imaging Retina. 2019;50:208-214.].

MeSH terms

  • Female
  • Follow-Up Studies
  • Forecasting*
  • Gestational Age
  • Humans
  • Infant, Newborn
  • Male
  • Ophthalmoscopy / methods*
  • Retina / diagnostic imaging*
  • Retinopathy of Prematurity / diagnosis
  • Retinopathy of Prematurity / surgery*
  • Retrospective Studies
  • Severity of Illness Index
  • Visual Acuity*
  • Vitrectomy / methods*