[Acute kidney injury: from creatinine to KIM‑1?]

Internist (Berl). 2019 Jun;60(6):578-586. doi: 10.1007/s00108-019-0602-y.
[Article in German]


In addition to the early detection of an acute kidney injury (AKI), several problems or questions have to be addressed. These include the identification of the etiology, the severity (functional or structural), the prognosis (recovery or transition to chronic renal failure), the course of the disease (dialysis or not), and the identification of specific treatment options for AKI. The following article provides an overview of established and new AKI biomarkers as well as an outlook on the potential of future biomarker-associated models of AKI.

Keywords: Biomarkers; Epigenetics; Kidney damage, functional; Kidney damage, structural; Proteomics.

Publication types

  • Review

MeSH terms

  • Acute Kidney Injury / blood*
  • Acute Kidney Injury / therapy
  • Acute Kidney Injury / urine*
  • Biomarkers / blood*
  • Biomarkers / urine*
  • Creatinine
  • Humans
  • Renal Dialysis
  • Renal Insufficiency, Chronic / complications


  • Biomarkers
  • Creatinine