What is needed now for successful scale-up of screening?

Papillomavirus Res. 2019 Jun:7:173-175. doi: 10.1016/j.pvr.2019.04.011. Epub 2019 Apr 16.


Effective screening for pre-cancerous lesions of the cervix is the only protective intervention that can be offered to women that have not had the opportunity to be vaccinated. Elimination goals are being developed so that by 2030, 70% of women aged 35-45 years should have been screened at least once in a lifetime and 90% of all detected lesions should have been treated. These goals focus on a substantial reduction of cervical cancer burden in low- and middle-income countries (LMICs). Scaling-up screening in these settings may be substantially improved by using self-sampling (SS), human papillomavirus (HPV) testing, and managing screened-positive women with accessible treatment. The implementation of these tools requires minimal health information data for traceability, provider training, community education, operational management and quality control. Cost-effective algorithms tailored to country needs can greatly impact the burden of disease in a limited number of years.

Keywords: Barriers; Cervical cancer; Follow-up; HPV; Health information system; Screening.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adult
  • Diagnostic Services / organization & administration*
  • Disease Eradication / organization & administration
  • Early Detection of Cancer / methods*
  • Female
  • Humans
  • Middle Aged
  • Papillomaviridae / isolation & purification*
  • Papillomavirus Infections / complications*
  • Precancerous Conditions / diagnosis*
  • Uterine Cervical Neoplasms / prevention & control*