Investigation of smell and taste function in patients with obstructive sleep apnoea syndrome

J Laryngol Otol. 2019 May;133(5):376-379. doi: 10.1017/S0022215119000768. Epub 2019 Apr 22.

Abstract

Objective: This study investigated the relationship between disease severity and taste and smell functions in patients with obstructive sleep apnoea syndrome.

Methods: A total of 65 patients with recurrent upper airway obstruction during sleep were included. Participants were divided into four groups according to apnoea-hypopnoea index, obtained on polysomnography. Smell and taste tests were performed on these patients.

Results: A significant difference was observed between the smell thresholds of the groups for the identification test (p = 0.016). In the taste test, significant differences were observed between the groups in terms of sweet, sour, salty and bitter taste test thresholds (p = 0.029, p = 0.0005, p = 0.001 and p = 0.017, respectively).

Conclusion: As sleep apnoea severity increased (according to the apnoea-hypopnoea index) in obstructive sleep apnoea syndrome patients, the taste and smell thresholds decreased due to the effect of neuropathy and inflammation in the upper respiratory tract.

Keywords: Inflammation; Obstructive Sleep Apnea Syndrome; Sense of Smell; Taste Sense.

MeSH terms

  • Adult
  • Female
  • Humans
  • Inflammation
  • Male
  • Middle Aged
  • Polysomnography
  • Prospective Studies
  • Sensory Thresholds / physiology*
  • Severity of Illness Index
  • Sleep
  • Sleep Apnea, Obstructive / physiopathology*
  • Smell / physiology*
  • Taste / physiology*