Depression involved in self-reported prospective memory problems in survivors of breast cancer who have received chemotherapy

Medicine (Baltimore). 2019 Apr;98(16):e15301. doi: 10.1097/MD.0000000000015301.

Abstract

To investigate the relationship between depression and the self-reported prospective memory (SPM) problems in breast cancer survivors who have received chemotherapy.Sixty-three breast cancer patients were administered with self-rating depression scale (SDS) and the prospective memory questionnaire as part of extensive neuropsychological assessments before and after chemotherapy. The performance of SDS and SPM were compared, with the level of significance set at P < .05.Compared with the group before chemotherapy, there is a significant difference on the SPM score (t = 6.069, P = .000) in breast cancer patients after chemotherapy. Further, there is also a significant difference on the SPM score (t = -4.348, P = .000) between the patients with and without depression group after chemotherapy.The present result indicated that the depression in breast cancer survivors after chemotherapy may be involved in their chemotherapy-induced SPM impairment.

MeSH terms

  • Antineoplastic Agents / adverse effects*
  • Antineoplastic Agents / therapeutic use
  • Breast Neoplasms / complications
  • Breast Neoplasms / drug therapy
  • Breast Neoplasms / psychology*
  • Cancer Survivors / psychology*
  • Case-Control Studies
  • Depression / etiology*
  • Female
  • Humans
  • Memory Disorders / chemically induced
  • Memory Disorders / etiology*
  • Memory, Episodic*
  • Middle Aged
  • Neuropsychological Tests
  • Psychiatric Status Rating Scales
  • Self Report

Substances

  • Antineoplastic Agents