Neurofibromatosis Presenting With Aqueductal Stenosis Due to a Tumor of the Aqueduct: Case Report

Neurosurgery. 1986 Dec;19(6):1035-7. doi: 10.1227/00006123-198612000-00024.


A 17-year-old boy with neurofibromatosis presented with delayed puberty and epileptic seizures of recent onset. A computed tomographic scan revealed aqueductal stenosis due to a tumor of the aqueduct. This tumor was found at autopsy to be a pilocytic astrocytoma. Aqueductal stenosis in neurofibromatosis is uncommon and has been considered to be a result of periaqueductal gliosis. This seems to be the first report of neurofibromatosis associated with a tumor of the aqueduct.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Astrocytoma / pathology
  • Cerebral Aqueduct / pathology*
  • Cerebral Ventricle Neoplasms / pathology*
  • Constriction, Pathologic / pathology
  • Humans
  • Hydrocephalus / pathology
  • Intracranial Pressure
  • Male
  • Neurofibromatosis 1 / pathology*
  • Tomography, X-Ray Computed