Treatment of Viral Infections During Pregnancy

Clin Perinatol. 2019 Jun;46(2):235-256. doi: 10.1016/j.clp.2019.02.009. Epub 2019 Mar 28.


Viral infections are common complications of pregnancy. Although some infections have maternal sequelae, many viral infections can be perinatally transmitted to cause congenital or chronic infection in fetuses or infants. Treatments of such infections are geared toward reducing maternal symptoms and complications and toward preventing maternal-to-child transmission of viruses. This article reviews the treatment of herpes simplex virus, cytomegalovirus, hepatitis B and C viruses, and human immunodeficiency virus during pregnancy.

Keywords: Antiviral therapy; Cytomegalovirus; Herpes simplex virus; Human immunodeficiency virus; Maternal-to-child transmission; Pregnancy; Viral hepatitis; Viral infections.

Publication types

  • Review

MeSH terms

  • Antiviral Agents / therapeutic use*
  • Cytomegalovirus Infections / drug therapy*
  • Female
  • HIV Infections / drug therapy*
  • Hepatitis B, Chronic / drug therapy*
  • Hepatitis C, Chronic / drug therapy*
  • Herpes Simplex / drug therapy*
  • Humans
  • Infant, Newborn
  • Infectious Disease Transmission, Vertical / prevention & control*
  • Maternal-Fetal Exchange
  • Pregnancy
  • Pregnancy Complications, Infectious / drug therapy*


  • Antiviral Agents