Overcoming mitomycin C resistance with semisynthetic derivatives

Prog Clin Biol Res. 1986:223:63-79.
No abstract available

MeSH terms

  • Animals
  • Biotransformation
  • Carcinoma / drug therapy*
  • Cell Line
  • Colonic Neoplasms / drug therapy*
  • DNA / metabolism
  • Drug Resistance
  • Humans
  • Mice
  • Mitomycin
  • Mitomycins / metabolism
  • Mitomycins / pharmacology*
  • Neoplasm Transplantation
  • Structure-Activity Relationship
  • Transplantation, Heterologous

Substances

  • Mitomycins
  • Mitomycin
  • N(6)-((dimethylamino)methylene)mitomycin C
  • DNA