Effect of ginger (Zingiber officinale) on semen quality

Andrologia. 2019 Jul;51(6):e13296. doi: 10.1111/and.13296. Epub 2019 Apr 22.


To date, according to the Scopus database, the biological effects of ginger (binominal name: Zingiber officinale), or ginger extracts, and its derived compounds on semen quality and sperm parameters have been revealed in more than 35 original articles. Though, still, there are no collective systematic or narrative discussion and conclusion of this specific research streak. Here, we systematically review and summarise the current link between ginger and its bioactive compounds with semen quality. To achieve this, we searched the central databases (Scopus and PubMed) for original studies, published in English language from August 2004 through February 2019 using the keywords "ginger" versus "sperm" and "semen." In summary, there is solid evidence that ginger enhances semen quality and improves the main sperm parameters such as concentration, viability, motility and morphology. Such beneficial effects of ginger on semen quality are attributable, at least in part, to increased levels of gonadal hormones, in particular, testosterone and luteinising hormone, decreased oxidative damage to cells, increased production of nitric oxide, hypoglycaemic response of ginger and the presence of valued nutrients in ginger such as manganese. Still, the positive effects of ginger on semen quality require additional approval in men.

Keywords: ginger; morphology; motility; semen quality; spermatozoon; viability.

Publication types

  • Systematic Review

MeSH terms

  • Animals
  • Blood Glucose / drug effects
  • Cell Survival / drug effects
  • Ginger / chemistry*
  • Humans
  • Luteinizing Hormone / metabolism
  • Male
  • Nitric Oxide / metabolism
  • Oxidation-Reduction / drug effects
  • Plant Extracts / pharmacology*
  • Sperm Motility / drug effects
  • Spermatozoa / drug effects*
  • Testis / drug effects*
  • Testis / metabolism
  • Testosterone / metabolism


  • Blood Glucose
  • Plant Extracts
  • Nitric Oxide
  • Testosterone
  • Luteinizing Hormone