Invasive management of symptomatic hepatic hemangioma

Eur J Gastroenterol Hepatol. 2019 Sep;31(9):1079-1084. doi: 10.1097/MEG.0000000000001413.


Hepatic hemangioma is common among benign liver tumors and usually grows slowly. About 50-70% of hepatic hemangiomas are asymptomatic, and management is not necessary; however, management should be considered in symptomatic patients. The optimal management of symptomatic hepatic hemangioma depends on multiple factors. Invasive management of symptomatic hepatic hemangioma mainly consists of surgery and interventional radiology, including transarterial embolization, ablation, percutaneous sclerotherapy, and percutaneous argon-helium cryotherapy. Although both surgery and interventional radiology are promising in the management of symptomatic hepatic hemangioma, multiple and/or giant hemangiomas represent a clinical dilemma because the complication rate and recurrence rate are relatively high, and symptom relief is not always achieved. However, a review of recent advances in treatment is lacking. We therefore summarized the current invasive management techniques for symptomatic hepatic hemangioma to potentially facilitate clinical decision-making.

Publication types

  • Review

MeSH terms

  • Cryotherapy
  • Embolization, Therapeutic
  • Hemangioma / complications
  • Hemangioma / diagnosis
  • Hemangioma / therapy*
  • Humans
  • Liver Neoplasms / complications
  • Liver Neoplasms / diagnosis
  • Liver Neoplasms / therapy*
  • Sclerotherapy