JEDI (jugular entrapment, dilated ventricles, intracranial hypertension) syndrome: a new clinical entity? A case report

Acta Neurochir (Wien). 2019 Jul;161(7):1367-1370. doi: 10.1007/s00701-019-03908-2. Epub 2019 Apr 25.

Abstract

Patients with idiopathic intracranial hypertension are frequently obese women with normal/slit ventricles. Patients with high-pressure hydrocephalus, instead, present enlarged ventricles. We describe a 63-year-old woman with signs and symptoms of intracranial hypertension. Brain MRI revealed hydrocephalus. Venous Doppler ultrasound showed external compression of the omohyoid muscles on the internal jugular veins. During jugular vein decompression, intracranial pressure dropped from 18 to 6 mmHg. Patient is asymptomatic at 2-year follow-up, with decreased brain ventricles. These findings could represent a novel form of high-pressure hydrocephalus that can be successfully treated without a CSF shunt. We called this syndrome JEDI (jugular entrapment dilated ventricles intracranial hypertension).

Keywords: Hydrocephalus; Intracranial hypertension; Jugular veins.

Publication types

  • Case Reports

MeSH terms

  • Cerebral Ventricles / diagnostic imaging
  • Female
  • Humans
  • Hydrocephalus / diagnostic imaging*
  • Hydrocephalus / pathology
  • Intracranial Hypertension / diagnostic imaging*
  • Intracranial Hypertension / pathology
  • Jugular Veins / diagnostic imaging
  • Magnetic Resonance Imaging
  • Middle Aged
  • Pseudotumor Cerebri / diagnostic imaging*
  • Pseudotumor Cerebri / pathology
  • Syndrome
  • Ultrasonography, Doppler, Transcranial