Etiology of Gender Identity

Endocrinol Metab Clin North Am. 2019 Jun;48(2):323-329. doi: 10.1016/j.ecl.2019.01.002. Epub 2019 Mar 18.

Abstract

This article reviews the current literature characterizing potential factors associated with the etiologies of gender identity. The PubMed database was searched for all literature that assessed key elements affecting development of gender identity. Current models attribute gender identity etiology to endogenous biology along with prenatal androgen exposure. However, no genetic loci or specific neuroanatomic regions have been consistently identified as the single explanation for transgender identity. Although environment may play a role in gender expression, there are no data to suggest an exogenous explanation for the development of gender identity.

Keywords: Etiology; Gender expression; Gender identity; Transgender.

Publication types

  • Systematic Review

MeSH terms

  • Animals
  • Female
  • Gender Identity*
  • Humans
  • Male
  • Pregnancy
  • Transsexualism / etiology*