Ebola Virus Disease: Clinical Challenges, Recognition, and Management

Nurs Clin North Am. 2019 Jun;54(2):169-180. doi: 10.1016/j.cnur.2019.02.001. Epub 2019 Mar 26.


The 2014 to 2016 Ebola outbreak response resulted in many lessons learned about biocontainment patient care, leading to enhanced domestic capabilities for highly infectious and hazardous communicable diseases. However, additional opportunities for improvement remain. The article identifies and describes key considerations and challenges for laboratory analysis, clinical management, transportation, and personnel management during the care of patients infected with Ebola or other special pathogens. Dedication to maintaining preparedness enables biocontainment patient care teams to perform at the highest levels of safety and confidence.

Keywords: Biocontainment; Biosecurity; Clinical management; Ebola virus; Emerging diseases.

Publication types

  • Review

MeSH terms

  • Africa, Western
  • Containment of Biohazards / standards*
  • Disease Outbreaks / prevention & control*
  • Guidelines as Topic*
  • Hemorrhagic Fever, Ebola / diagnosis*
  • Hemorrhagic Fever, Ebola / therapy*
  • Humans
  • Security Measures / standards*
  • United States