Framework for patient-ventilator asynchrony during long-term non-invasive ventilation

Thorax. 2019 Jul;74(7):715-717. doi: 10.1136/thoraxjnl-2018-213022. Epub 2019 Apr 26.


Episodes of patient-ventilator asynchrony (PVA) occur during acute and chronic non-invasive positive pressure ventilation (NIV). In long-term NIV, description and quantification of PVA is not standardised, thus limiting assessment of its clinical impact. The present report provides a framework for a systematic analysis of polygraphic recordings of patients under NIV for the detection and classification of PVA validated by bench testing. The algorithm described uses two different time windows: rate asynchrony and intracycle asynchrony. This approach should facilitate further studies on prevalence and clinical impact of PVA in long-term NIV.

Keywords: asynchrony; central sleep apnea; home ventilators; monitoring; non-invasive ventilation; obstructive sleep apnoea; polysomnography; sleep-disordered breathing.

MeSH terms

  • Algorithms
  • Humans
  • Hypercapnia / therapy
  • Monitoring, Physiologic / methods
  • Noninvasive Ventilation / adverse effects
  • Noninvasive Ventilation / methods*
  • Polysomnography
  • Respiratory Insufficiency / physiopathology
  • Respiratory Insufficiency / therapy*
  • Respiratory Physiological Phenomena
  • Signal Processing, Computer-Assisted