Is It Possible to Make a Correct Diagnosis of Lyme Disease on Symptoms Alone? Review of Key Issues and Public Health Implications

Am J Med. 2019 Oct;132(10):1148-1152. doi: 10.1016/j.amjmed.2019.04.001. Epub 2019 Apr 25.

Abstract

There is much confusion and misinformation about the diagnosis of Lyme disease, as well as its treatment. This review explains why one cannot make a correct diagnosis of Lyme disease based on symptoms alone. It also provides evidence to support the validity of two-tier testing for the laboratory diagnosis of Lyme disease. The public health consequences of failing to consider these issues are discussed.

Keywords: Diagnosis of Lyme disease; Lyme disease; Public health implications; Symptoms of Lyme disease; Treatment of Lyme disease.

Publication types

  • Review

MeSH terms

  • Clinical Laboratory Techniques / standards
  • Humans
  • Lyme Disease / diagnosis*
  • Lyme Disease / pathology*
  • Public Health*
  • Sensitivity and Specificity