Cardiac prostheses-related hemolytic anemia

Clin Cardiol. 2019 Jul;42(7):692-700. doi: 10.1002/clc.23191. Epub 2019 May 6.


Hemolysis is an unintended sequel of temporary or permanent intracardiac devices. However, limited data exist on the characteristics and treatment of hemolysis in patients with cardiac prostheses. This entity, albeit uncommon, often poses significant diagnostic and management challenges to the clinical cardiologist. In this article, we aim to provide a contemporary overview of the incidence, mechanisms, diagnosis, and management of cardiac prosthesis-related hemolysis.

Keywords: anemia; cardiac prosthesis; hemolysis; left ventricular assist device; paravalvular leak.

Publication types

  • Review

MeSH terms

  • Anemia, Hemolytic / epidemiology
  • Anemia, Hemolytic / etiology*
  • Global Health
  • Heart Valve Prosthesis / adverse effects*
  • Heart Valve Prosthesis Implantation / adverse effects*
  • Humans
  • Incidence