Assessment of the response of hepatocellular carcinoma to interventional radiology treatments

Future Oncol. 2019 May;15(15):1791-1804. doi: 10.2217/fon-2018-0747. Epub 2019 May 2.

Abstract

According to Barcelona Clinic Liver Cancer (BCLC) guidelines, interventional radiology procedures are valuable treatment options for many hepatocellular carcinomas (HCCs) that are not amenable to resection or transplantation. Accurate assessment of the efficacy of therapies at earlier stages enables completion of treatment, optimal follow-up and to prevent potentially unnecessary treatments, side effects and costly failure. The goal of this review is to summarize and describe the radiological strategies that have been proposed to predict survival and to stratify HCC responses after interventional radiology therapies. New techniques currently in development are also described.

Keywords: HCC; TACE; imaging; interventional radiology; response criteria.

MeSH terms

  • Carcinoma, Hepatocellular / diagnosis
  • Carcinoma, Hepatocellular / mortality
  • Carcinoma, Hepatocellular / radiotherapy*
  • Diagnostic Imaging
  • Disease Management
  • Humans
  • Liver Neoplasms / diagnosis
  • Liver Neoplasms / mortality
  • Liver Neoplasms / radiotherapy*
  • Neoplasm Staging
  • Radiology, Interventional
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • Tumor Burden