Malignant lymphoma of the oral cavity: clinicopathologic analysis of 20 cases

J Oral Pathol. 1987 Jan;16(1):8-12. doi: 10.1111/j.1600-0714.1987.tb00669.x.

Abstract

Twenty cases of malignant lymphomas (ML) of the oral cavity were reviewed in the light of recent histologic classification. They occurred in 12 male and 8 female patients, with the age range of 11-80 years (median 51 years of age). Eighty percent of patients were stages IE and IIE. Histologically, 15 cases (75%) were ordinary non-Hodgkin's lymphoma (NHL) with diffuse large cell type being the most common. The remaining 5 cases, undefinable by classification scheme for ordinary NHL, were designated as malignant histiocytosis of the oral cavity (3 cases) and peripheral T-cell lymphoma (2 cases), respectively. There were no cases of follicular lymphoma. The present cases comprised 45% of high grade, 40% of intermediate grade, and 15% of low grade malignancy. A follow-up study showed that the stage of diseage, histologic classification, and frequency of mitosis correlated well with survival.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Child
  • Female
  • Follow-Up Studies
  • Gingival Neoplasms / pathology
  • Humans
  • Lymphoma / mortality
  • Lymphoma / pathology*
  • Male
  • Mandibular Neoplasms / pathology
  • Middle Aged
  • Mouth Floor
  • Mouth Neoplasms / mortality
  • Mouth Neoplasms / pathology*
  • Prognosis