Phase Separation Comes of Age: From Phenomenology to Single Molecules

Aritra Chowdhury; Miao Yu; Edward A Lemke

doi:10.1016/j.molcel.2019.04.016

Phase Separation Comes of Age: From Phenomenology to Single Molecules

Mol Cell. 2019 May 2;74(3):413-415. doi: 10.1016/j.molcel.2019.04.016.

Authors

Aritra Chowdhury¹, Miao Yu², Edward A Lemke³

Affiliations

¹ Structural and Computational Biology Unit, Cell Biology and Biophysics Unit, EMBL, Meyerhofstrasse1, 69117 Heidelberg, Germany.
² Biocenter Mainz, Departments of Biology and Chemistry, Johannes Gutenberg University, Hanns-Dieter-Hüsch-Weg 15, 55128 Mainz, Germany; Institute of Molecular Biology, Ackermannweg 10, 55128 Mainz, Germany; Structural and Computational Biology Unit, Cell Biology and Biophysics Unit, EMBL, Meyerhofstrasse1, 69117 Heidelberg, Germany.
³ Biocenter Mainz, Departments of Biology and Chemistry, Johannes Gutenberg University, Hanns-Dieter-Hüsch-Weg 15, 55128 Mainz, Germany; Institute of Molecular Biology, Ackermannweg 10, 55128 Mainz, Germany; Structural and Computational Biology Unit, Cell Biology and Biophysics Unit, EMBL, Meyerhofstrasse1, 69117 Heidelberg, Germany. Electronic address: edlemke@uni-mainz.de.

PMID: 31051137
DOI: 10.1016/j.molcel.2019.04.016

Abstract

In this issue of Molecular Cell, Pitchiaya et al. (2019) use high-resolution single-molecule microscopy to dissect the localization of different types of RNAs with processing bodies (PBs) in cells, revealing novel insights about their dynamic recruitment to PBs.

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MeSH terms

Nanotechnology*
RNA*
Single Molecule Imaging

Substances

RNA