New site-specific anatomical defects discovered within the female urogenital tract

Eur J Obstet Gynecol Reprod Biol. 2019 Jun;237:164-169. doi: 10.1016/j.ejogrb.2019.04.019. Epub 2019 Apr 23.

Abstract

Objectives: Testing whether the site-specific anatomical defect(s) can occur within the urethral stabilizing mechanism; determining the anatomical structure compositions of the urethral stabilizing mechanism.

Study design: In an international setting, fifteen human fresh female cadavers subjected to urogenital tract stratum-by-stratum macro- and micro-dissection and a case series study type utilized in this scientific research. The primary outcome measured occurrences of anatomical site-specific defects within the urethral stabilizing mechanism and the secondary outcome measured the anatomical structures of the urethral stabilizing mechanism.

Results: Site-specific defects occurred within the urethral stabilizing mechanism in four out of fifteen subjects (26.6%); defects most commonly identified within suburethral-paraurethral-periurethral areas. The ventral perineal membrane and distal condensations of the arcus tendineus levatoris ani defects were also present. The urethral stabilizing mechanism consists of multiple anatomical structures located in different anatomical regions.

Conclusions: Site-specific defects occur within the urethral stabilizing mechanism in women. The urethral stabilizing mechanism consists of multiple anatomical structures located in different anatomical regions, and they fuse with the urethral wall.

Keywords: Female urethral anatomy; Stress urinary incontinence; Urethral anatomical defects; Urethral site-specific defects; Urethral stabilizing mechanism; Urethral stabilizing mechanism defects.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Dissection
  • Female
  • Humans
  • Middle Aged
  • Urethra / abnormalities*
  • Urogenital Abnormalities / pathology*