Maternal sensitization occurs before delivery in severe cases of fetal alloimmune thrombocytopenia

Am J Hematol. 2019 Aug;94(8):E213-E215. doi: 10.1002/ajh.25503. Epub 2019 May 16.

Authors

Jenny C Jin¹, Madhavi M Lakkaraja¹, Polina Ferd¹, Karen Manotas¹, Julia Gabor¹, Megan Wissert¹, Richard L Berkowitz², Janice G McFarland³, James B Bussel¹

Affiliations

¹ Department of Pediatric Hematology/Oncology, New York Presbyterian Hospital/Weill Cornell Medical College, New York City, New York.
² Department of Obstetrics and Gynecology, Columbia University Medical Center, New York City, New York.
³ Platelet and Neutrophil Immunology Laboratory, Blood Center of Wisconsin, Milwaukee, Wisconsin.

PMID: 31056760
DOI: 10.1002/ajh.25503

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Antigens, Human Platelet / immunology*
Female
Histocompatibility, Maternal-Fetal / immunology*
Humans
Infant, Newborn
Integrin beta3
Maternal-Fetal Exchange / immunology*
Pregnancy / immunology
Severity of Illness Index
Thrombocytopenia, Neonatal Alloimmune / immunology*
Young Adult

Substances

Antigens, Human Platelet
ITGB3 protein, human
Integrin beta3