First-line management of metastatic non-small cell lung cancer: An Indian perspective

South Asian J Cancer. 2019 Apr-Jun;8(2):73-79. doi: 10.4103/sajc.sajc_294_18.


Lung cancer has been the most common cancer in the world for several decades. The non-small cell lung cancer (NSCLC) constitutes approximately about 80% of the total cases of lung cancer. Therapeutic interventions in NSCLC have shifted to the target-based approach from histology-based approach, and this has completely changed the face of the management of NSCLC. Developing countries, such as India, have very limited data compiled about the prevalence and treatment practices of lung cancer, despite a large burden of the disease. However, in recent times, there has been a lot of data generated in this regard. This article is an attempt to collate and shine light on the available data for the first-line treatment of NSCLC in India keeping in mind the current standards of care in this area.

Keywords: Advanced non-small cell lung cancer; anaplastic lymphoma kinase; chemotherapy; epidermal growth factor receptor; tyrosine kinase inhibitor.

Publication types

  • Review