Future directions in endometriosis treatment: discovery and development of novel inhibitors of estrogen biosynthesis

Expert Opin Investig Drugs. 2019 Jun;28(6):501-504. doi: 10.1080/13543784.2019.1618269. Epub 2019 May 17.

Fabio Barra^{1

2}, Andrea Romano³, Giovanni Grandi⁴, Fabio Facchinetti⁴, Simone Ferrero^{1

2}

¹ a Academic Unit of Obstetrics and Gynecology , IRCCS Ospedale Policlinico San Martino , Genoa , Italy.
² b Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DiNOGMI) , University of Genoa , Genoa Italy.
³ c Department of Gynaecology and Obstetrics, GROW - School for Oncology & Developmental Biology , Maastricht University , Maastricht , the Netherlands.
⁴ d Department of Obstetrics, Gynecology and Pediatrics, Obstetrics and Gynecology Unit, Azienda Ospedaliero-Universitaria Policlinico , University of Modena and Reggio Emilia , Modena , Italy.

No abstract available

Keywords: 17β-hydroxysteroid dehydrogenase 1; AKR1C3; Endometriosis; aromatase inhibitors; estrogen biosynthesis; steroid sulphatase.

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