The Yellow Brick Road towards HIV Eradication

Asier Saez-Cirion; Michaela Müller-Trutwin

doi:10.1016/j.it.2019.04.006

The Yellow Brick Road towards HIV Eradication

Trends Immunol. 2019 Jun;40(6):465-467. doi: 10.1016/j.it.2019.04.006. Epub 2019 May 6.

Authors

Asier Saez-Cirion¹, Michaela Müller-Trutwin²

Affiliations

¹ Institut Pasteur, HIV Inflammation and Persistence Unit, 75015 Paris, France.
² Institut Pasteur, HIV Inflammation and Persistence Unit, 75015 Paris, France. Electronic address: mmuller@pasteur.fr.

PMID: 31072685
DOI: 10.1016/j.it.2019.04.006

Abstract

A London patient living with HIV-1 has become the second person to achieve remission from HIV-1 infection for >1 year after receiving a bone marrow stem cell transplant from a donor with cells resistant to CCR5-tropic HIV-1 infection (Gupta et al. Nature 2019;568:244-248). This case provides important clues in the uncertain path towards an HIV cure.

Publication types

Research Support, Non-U.S. Gov't
Comment

MeSH terms

HIV Infections*
HIV-1*
Hematopoietic Stem Cell Transplantation*
Humans
Receptors, CCR5

Substances

Receptors, CCR5