Metastatic squamous cell carcinoma of penis in an HIV-infected man presenting with cutaneous manifestations

Int J STD AIDS. 2019 May;30(6):613-616. doi: 10.1177/0956462418813069. Epub 2019 Feb 4.

Abstract

The incidence of penile squamous cell carcinoma (SCC) varies widely in different parts of the world. It is rare in Western countries but common in developing countries like India. The glans and foreskin are the most commonly affected sites. It can occur in two forms which have different evolution and prognosis. Exophytic papillary lesions have late and rare lymphatic spread and ulcero-infiltrating lesions are associated with rapid lymph node invasion and a poorer prognosis. Human immunodeficiency virus (HIV) is an aggravating factor for penile cancer and accelerates the progression of the disease. Cutaneous metastasis from penile SCC is rarely reported. Here, we report a case of metastatic SCC of the penis in a 51-year-old HIV-infected man who presented with cutaneous metastases in the inguino-pubic region with a hidden penile SCC.

Keywords: HIV; Metastatic squamous cell carcinoma; penis.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Agents / therapeutic use
  • Carcinoma, Squamous Cell / drug therapy
  • Carcinoma, Squamous Cell / pathology*
  • Fatal Outcome
  • HIV Infections / complications*
  • Humans
  • Lymph Nodes / pathology
  • Male
  • Middle Aged
  • Penile Neoplasms / drug therapy
  • Penile Neoplasms / pathology*
  • Phimosis
  • Skin Neoplasms / pathology
  • Skin Neoplasms / secondary*

Substances

  • Antineoplastic Agents