Medications and Vocal Function

Otolaryngol Clin North Am. 2019 Aug;52(4):693-702. doi: 10.1016/j.otc.2019.03.013. Epub 2019 May 7.

Abstract

Medications can have innumerable direct and indirect effects on laryngeal hydration, vocal fold mucosal integrity, laryngeal muscle function, and laryngeal sensation. Effects, therefore, can be subtle and slowly progressive over time. This article delineates the general classes of medications that are known to cause alterations of vocal function, highlights medical history symptoms that may help raise suspicion for medication-related vocal changes, and presents recommendations for approaches to treatment of these issues.

Keywords: Anticholinergic; Antipsychotic; Dysphonia; Medications; Reflux; Steroid inhaler.

Publication types

  • Review

MeSH terms

  • Drug-Related Side Effects and Adverse Reactions*
  • Dysphonia / etiology*
  • Dysphonia / physiopathology*
  • Humans
  • Laryngopharyngeal Reflux / diagnosis
  • Laryngopharyngeal Reflux / drug therapy
  • Pharmaceutical Preparations
  • Vocal Cords / physiopathology
  • Voice Quality / drug effects

Substances

  • Pharmaceutical Preparations