doi: 10.1016/0006-8993(87)90731-1.
The central amygdala and immobilization stress-induced gastric pathology in rats: neurotensin and dopamine
- PMID: 3107755
- DOI: 10.1016/0006-8993(87)90731-1
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The central amygdala and immobilization stress-induced gastric pathology in rats: neurotensin and dopamine
Brain Res.
.
Abstract
Bilateral microinjections of neurotensin (3, 10 and 30 micrograms) into the central amygdala had a dose-related attenuating effect on cold-restraint gastric ulcers in rats. Similar inhibitory effects were also observed with intra-amygdalar dopamine (3, 10 and 30 micrograms). Pretreatment with 6-hydroxydopamine (10 micrograms) or haloperidol (1 mg/kg), however, reversed the ulcer attenuating effect of neurotensin. The results indicate that the central amygdala is important in the mediation of the cytoprotective effects of neurotensin and dopamine.
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