Pulmonary Hypertension and Exercise

James R Vallerand; Jason Weatherald; Pierantonio Laveneziana

doi:10.1016/j.ccm.2019.02.003

Pulmonary Hypertension and Exercise

Clin Chest Med. 2019 Jun;40(2):459-469. doi: 10.1016/j.ccm.2019.02.003.

Authors

James R Vallerand¹, Jason Weatherald², Pierantonio Laveneziana³

Affiliations

¹ Undergraduate Medical Education, Cumming School of Medicine, University of Calgary, 3330 Hospital Drive Northwest G702, Calgary, Alberta T2N 4N1, Canada.
² Division of Respiratory Medicine, Department of Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; Libin Cardiovascular Institute of Alberta, Calgary, Alberta, Canada; Peter Lougheed Centre, 3500 26 Avenue Northeast, Calgary, Alberta T1Y 6J4, Canada.
³ Sorbonne Universités, Université Pierre et Marie Curie Université Paris 06, Institut National de la Santé et de la Recherche Médicale, Unité Mixte de Recherche S_1158 Neurophysiologie Respiratoire Expérimentale et Clinique, Paris, France; Service des Explorations Fonctionnelles de la Respiration, de l'Exercice et de la Dyspnée Hôpital Universitaire Pitié-Salpêtrière (AP-HP), Département Respiration, Réanimation, Réhabilitation, Sommeil, Pôle PRAGUES, Groupe Hospitalier Pitié-Salpêtrière Charles Foix, Assistance Publique-Höpitaux de Paris, Paris, France. Electronic address: pierantonio.laveneziana@psl.aphp.fr.

PMID: 31078222
DOI: 10.1016/j.ccm.2019.02.003

Abstract

Cardiopulmonary exercise testing can be a useful tool for clinicians working with pulmonary hypertension (PH) patients. Exercise magnifies numerous cardiopulmonary decompensations, which can help inform diagnoses, assess degrees of physical impairment, evaluate exertional dyspnea, and estimate prognoses for PH patients. Supervised exercise training also holds promise in PH, because it is safe for patients and feasible and may improve key prognostic outcomes that relate to improvements in quality of life and survival. Still, few clinical trials have evaluated the potential therapeutic effects of exercise training, and future trials may benefit from integrating programming that focuses on light-intensity endurance, strength, and respiratory training.

Keywords: Cardiopulmonary exercise testing; Chronic thromboembolic pulmonary hypertension; Dyspnea; Pulmonary arterial hypertension; Pulmonary vascular disease.

Publication types

Review

MeSH terms

Exercise / physiology*
Exercise Test / methods*
Female
Humans
Hypertension, Pulmonary / diagnosis*
Male