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. 2019 Jan 28;4(5):720-723.
doi: 10.1016/j.ekir.2019.01.009. eCollection 2019 May.

Metabolomic Patterns in Adolescents With Mild to Moderate CKD

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Free PMC article

Metabolomic Patterns in Adolescents With Mild to Moderate CKD

Ellen R Brooks et al. Kidney Int Rep. .
Free PMC article

Figures

Figure 1
Figure 1
(a–j) Plasma metabolites and ratios differ significantly between chronic kidney disease (CKD) cohorts (stages 2 and 3b; n = 20/group; false discovery rate <0.05). ADMA, asymmetric dimethylarginine; Cit, citrulline; Cr, creatinine; C4:1, butenoylcarnitine (fatty acylcarnitine); FDR, false discovery rate (5% of significant tests will result in false positives); Kyn, kynurenine; Orn, ornithine; PC ae (C32:1), phosphatidylcholine with acyl-akyl residue; Pro, proline; SDMA, symmetric dimethylarginine; Trp, tryptophan; Tyr, tyrosine.

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References

    1. Grams M.E., Tin A., Rebholz C.M. Metabolomic alterations associated with cause of CKD. Clin J Am Soc Nephrol. 2017;12:1787–1794. - PMC - PubMed
    1. Hu J.-R., Coresh J., Inker L.A. Serum metabolites are associated with all-cause mortality in chronic kidney disease. Kidney Int. 2018;94:381–389. - PMC - PubMed
    1. Kidney Disease: Improving Global Outcomes (KDIGO) Summary of recommendation statements: definition and classification of CKD. Kidney Int Suppl. 2013;3:5–7.
    1. Duranton F., Lundin U., Gayrard N. Plasma and urinary amino acid metabolomics profiling in patients with different levels of kidney function. Clin J Am Soc Nephrol. 2014;9:37–45. - PMC - PubMed
    1. Koenig P., Nagl C., Neurauter G. Enhanced degradation of tryptophan in patients on hemodialysis. Clin Nephrol. 2010;74:465–470. - PubMed
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