Survey of motion sickness susceptibility in children and adolescents aged 3 months to 18 years

J Neurol. 2019 Sep;266(Suppl 1):65-73. doi: 10.1007/s00415-019-09333-w. Epub 2019 May 13.

Abstract

We conducted two representative, cross-sectional, population-based surveys on the susceptibility to motion sickness (MSS) in childhood: One was targeted at parents with children aged 6 months to 18 years (7569 households approached) and the other at parents with children aged 3 months to 5 years (12,720 households approached). In both surveys 3285 parents provided information on 5041 children. The main findings in the first survey were: 369 children (9.2%) were susceptible to motion sickness with a slight female preponderance, and in the second study 16 (1.2%) were susceptible; first occurrence of motion sickness (MS) below the age of 1 year was exceptionally rare (n = 2); if MS occurred after the age of 1 year it was more severe in the younger children, most pronounced between the age of 6 and 9 years; the frequency of MSS was highest in the range between the age of 4 and 13 years; in postpubertal children and adolescents MSS frequency declined. The course of MSS frequency from infancy to adolescence is an inverse U-shaped curve. It is characterised by three phases which may be related to the visual-vestibular mismatch theory, the major pathophysiological cause of MS. Phase one is a high resistance in the first year of life. In this phase infants may be less subject to visual-vestibular mismatch, because they do not yet use visual cues for self-motion perception. Phase two is a prepubertal peak. This is possibly due to an oversensitivity to a visual-vestibular mismatch, which reflects sensorimotor maturation. Phase three is a postpubertal decline. This can be explained by habituation through repetitive motion stimulation during various kinds of vehicle transportations.

Keywords: Car transportation; Children; Epidemiology; Motion sickness susceptibility; Sensory mismatch theory; Ship transportation.

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Cross-Sectional Studies
  • Disease Susceptibility / diagnosis
  • Disease Susceptibility / epidemiology
  • Female
  • Humans
  • Infant
  • Male
  • Motion Sickness / diagnosis*
  • Motion Sickness / epidemiology*
  • Retrospective Studies
  • Surveys and Questionnaires*