Micro/Nanoparticle Delivery Systems for Ocular Diseases

Assay Drug Dev Technol. 2019 May/Jun;17(4):152-166. doi: 10.1089/adt.2018.911. Epub 2019 May 15.

Abstract

Micro- (MPs) and nanoparticles (NPs) have been recently studied for their application in ophthalmic drug delivery. These drug delivery systems are able to circumvent the ocular barriers that currently limit the efficacy of conventional treatments, as well as provide a more sustained release of drug, reducing the frequency of administration and increasing patient compliance. This review summarizes the recent trends in ophthalmic research from conventional treatment to the utilization of MPs and NPs as drug carriers.

Keywords: drug delivery; microparticles; nanoparticles; neovascularization; ocular; polymers.

Publication types

  • Review

MeSH terms

  • Animals
  • Drug Carriers / chemistry
  • Drug Delivery Systems*
  • Dry Eye Syndromes / drug therapy*
  • Glaucoma / drug therapy*
  • Humans
  • Nanoparticles / chemistry*

Substances

  • Drug Carriers