[Research progress in saliva collection, analysis and its relationship with oral diseases]

Zhonghua Kou Qiang Yi Xue Za Zhi. 2019 May 9;54(5):344-349. doi: 10.3760/cma.j.issn.1002-0098.2019.05.010.
[Article in Chinese]


As one of the major body fluid, saliva has various components that can shift according to the systemic health state. With the atraumatic way of collection, saliva can be a promising media to help the detection of oral diseases. With the development of salivaomics and the application of unbiased, highly sensitive, and high throughout separation techniques for salivary components, there's now more possibilities for effective identification of biomarkers correlated with oral diseases. This review aimed to introduce the current state of saliva collection and detection techniques as well as their correlation with oral diseases, hoping to provide evidence for further research.


Keywords: Analysis of saliva; Mouth diseases; Saliva; Saliva collection.

Publication types

  • Review

MeSH terms

  • Biomarkers
  • Humans
  • Mouth Diseases* / diagnosis
  • Research
  • Saliva* / chemistry


  • Biomarkers