In this study, we present the youngest reported case of posterior reversible encephalopathy syndrome (PRES) in the United States, which developed following perforated appendicitis with subsequent peritonitis and intra-abdominal abscess formation. Additionally, we discuss potential physiological factors contributing to her acute neurological deterioration and resultant cerebral vasogenic edema.
Keywords: PRES; autoregulation; endothelium; seizures; sepsis.