Yunis-Varon Syndrome

J Ayub Med Coll Abbottabad. 2019 Apr-Jun;31(2):290-292.


Yunis-Varon syndrome is a rare autosomal recessive disorder with characteristic facial features and limb anomalies. We report a neonate born to consanguineously married normal parents with typical clinical and radiologic features of Yunis-Varon syndrome along with complete cleft lip and palate: an infrequent association. The family had two previous babies with similar features who died in infancy. This is a first reported case of Yunis-Varon syndrome in Pakistan.

Keywords: Cleidocranial dysplasia; Aplastic thumb and toes; Yunis-Varon syndrome.

Publication types

  • Case Reports

MeSH terms

  • Cleft Lip
  • Cleft Palate
  • Cleidocranial Dysplasia*
  • Consanguinity
  • Ectodermal Dysplasia*
  • Fatal Outcome
  • Female
  • Humans
  • Infant, Newborn
  • Limb Deformities, Congenital*
  • Micrognathism*
  • Pakistan

Supplementary concepts

  • Yunis Varon syndrome