Choriocapillary Blood Flow in Myopic Subjects Measured With OCT Angiography

Ophthalmic Surg Lasers Imaging Retina. 2019 May 1;50(5):e133-e139. doi: 10.3928/23258160-20190503-13.

Abstract

Background and objective: To investigate choriocapillary blood flow in myopic eyes using optical coherence tomography angiography.

Patients and methods: Seventy-eight myopic and 79 age-matched healthy eyes were included in this study, with myopia defined as a spherical equivalent refraction (SER) between -1 diopters (D) and -6 D. Quantitative measurements of the choriocapillaris were obtained using the Avanti RTVue XR with AngioVue. Choroidal thickness (CT) was assessed using the single-line enhanced high-definition scan of the same device.

Results: CT correlated positively with SER (P = .017) and negatively with bulbus axial length (AL) (P = .180). Subfoveal choriocapillary blood flow did not show any significant correlation with any of the parameters SER, AL, or CT (P = .798, P = .269, and P = .820, respectively). The mean flow signal of the myopic group did not differ significantly from the mean flow signal of the emmetropic control group (P = .266).

Conclusion: Choriocapillary blood flow seems to retain a constant level with increasing physiological myopia. [Ophthalmic Surg Lasers Imaging Retina. 2019;50:e133-e139.].

MeSH terms

  • Adult
  • Choroid / physiopathology*
  • Female
  • Fluorescein Angiography / methods*
  • Follow-Up Studies
  • Fundus Oculi
  • Healthy Volunteers
  • Humans
  • Male
  • Myopia / diagnosis
  • Myopia / physiopathology*
  • Refraction, Ocular / physiology
  • Regional Blood Flow / physiology*
  • Retrospective Studies
  • Tomography, Optical Coherence / methods*
  • Young Adult