Prevention of Infection After Cesarean Delivery

Clin Obstet Gynecol. 2019 Dec;62(4):758-770. doi: 10.1097/GRF.0000000000000460.


The critical measures of importance in reducing the frequency of postcesarean infection are preoperative cleansing of the vagina with a povidone-iodine solution, administration of cefazolin plus azithromycin before surgery, preparation of the abdomen with a chlorhexidine solution, removal of the placenta by traction on the cord, closure of the deep part of the subcutaneous layer, and closure of the skin with sutures rather than staples.

MeSH terms

  • Administration, Intravaginal
  • Anti-Infective Agents, Local / administration & dosage*
  • Antibiotic Prophylaxis / methods*
  • Cesarean Section / adverse effects*
  • Chlorhexidine / administration & dosage
  • Female
  • Humans
  • Povidone-Iodine / administration & dosage
  • Pregnancy
  • Preoperative Care / methods*
  • Surgical Wound Infection / prevention & control*
  • Vagina / microbiology


  • Anti-Infective Agents, Local
  • Povidone-Iodine
  • Chlorhexidine