An update on ecdysone signaling during insect oogenesis

Abstract

An overview is presented of the different functions of ecdysone signaling during insect oogenesis. An extensive genetic toolkit allowed analysis with unprecedented temporal and spatial detail in Drosophila where functions were revealed in stem cell proliferation and niche maintenance, germline cyst differentiation and follicle formation, integration of nutrient and lipid signaling, follicle maturation and ovulation. Besides putative autocrine/paracrine signaling, hormonal networks were identified that integrate ecdysone with other endocrine signaling pathways. In other insects, progress in oogenesis has lagged behind although recently RNAi emerged as a new tool to analyze gene function in ovaries in hemimetabolous insects and Tribolium.