Antidepressants, withdrawal, and addiction; where are we now?

J Psychopharmacol. 2019 Jun;33(6):655-659. doi: 10.1177/0269881119845799. Epub 2019 May 21.

Abstract

Controversy continues with regard to antidepressants and withdrawal. Recent debates have focused on the prevalence and length of withdrawal, and some continue to state that withdrawal from these compounds constitutes 'addiction'. In this editorial we examine the evidence underlying these recent debates. We acknowledge gaps in knowledge, and make suggestions for how the field can progress.

Keywords: Antidepressive agents; addiction; paroxetine; serotonin uptake inhibitors.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antidepressive Agents / adverse effects*
  • Antidepressive Agents / therapeutic use*
  • Behavior, Addictive / etiology*
  • Humans
  • Substance Withdrawal Syndrome / etiology*

Substances

  • Antidepressive Agents