Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2019 May;7(3).
doi: 10.1128/microbiolspec.GPP3-0025-2018.

Genomics and Genetics of Streptococcus pneumoniae


Genomics and Genetics of Streptococcus pneumoniae

Francesco Santoro et al. Microbiol Spectr. .


Ninety years after the discovery of pneumococcal Transformation, and 74 years after the work of Avery and colleagues that identified DNA as the genetic material, Streptococcus pneumoniae is still one of the most important model organism to understand Bacterial Genetics and Genomics. In this Chapter special emphasis has been given to Genomics and to Mobile Genetic Elements (the Mobilome) which greatly contribute to the dynamic variation of pneumococcal genomes by horizontal gene transfer. Other topics include molecular mechanisms of Genetic Transformation, Restriction/Modification Systems, Mismatch DNA Repair, and techniques for construction of genetically engineered pneumococcal strains.

Similar articles

See all similar articles

Cited by 1 article


LinkOut - more resources