Clinical use of intracoronary imaging. Part 2: acute coronary syndromes, ambiguous coronary angiography findings, and guiding interventional decision-making: an expert consensus document of the European Association of Percutaneous Cardiovascular Interventions

Eur Heart J. 2019 Aug 14;40(31):2566-2584. doi: 10.1093/eurheartj/ehz332.


This consensus document is the second of two reports summarizing the views of an expert panel organized by the European Association of Percutaneous Cardiovascular Interventions (EAPCI) on the clinical use of intracoronary imaging including intravascular ultrasound (IVUS), optical coherence tomography (OCT), and near infrared spectroscopy (NIRS)-IVUS. Beyond guidance of stent selection and optimization of deployment, invasive imaging facilitates angiographic interpretation and may guide treatment in acute coronary syndrome. Intravascular imaging can provide additional important diagnostic information when confronted with angiographically ambiguous lesions and allows assessment of plaque morphology enabling identification of vulnerability characteristics. This second document focuses on useful imaging features to identify culprit and vulnerable coronary plaque, which offers the interventional cardiologist guidance on when to adopt an intracoronary imaging-guided approach to the treatment of coronary artery disease and provides an appraisal of intravascular imaging-derived metrics to define the haemodynamic significance of coronary lesions.

Keywords: Acute coronary syndrome; Intravascular imaging; Intravascular ultrasound; Optical coherence tomography; Percutaneous coronary intervention.

MeSH terms

  • Acute Coronary Syndrome / diagnostic imaging*
  • Acute Coronary Syndrome / therapy
  • Adult
  • Aged
  • Case-Control Studies
  • Clinical Trials as Topic
  • Consensus
  • Coronary Angiography / methods
  • Coronary Angiography / trends*
  • Coronary Artery Disease / pathology
  • Coronary Artery Disease / therapy*
  • Decision Making
  • European Union / organization & administration
  • Female
  • Hemodynamics / physiology
  • Humans
  • Male
  • Middle Aged
  • Percutaneous Coronary Intervention / adverse effects*
  • Percutaneous Coronary Intervention / methods
  • Plaque, Atherosclerotic / pathology
  • Predictive Value of Tests
  • Rupture / diagnostic imaging
  • Spectroscopy, Near-Infrared / methods
  • Stents
  • Tomography, Optical Coherence / methods
  • Ultrasonography, Interventional / methods