Scratching Beneath the Surface: Linking Skin Pathology with Food Allergy

Marie Cherrier; Nadine Cerf-Bensussan

doi:10.1016/j.immuni.2019.04.013

Scratching Beneath the Surface: Linking Skin Pathology with Food Allergy

Immunity. 2019 May 21;50(5):1124-1126. doi: 10.1016/j.immuni.2019.04.013.

Authors

Marie Cherrier¹, Nadine Cerf-Bensussan²

Affiliations

¹ INSERM U1163 and Institut Imagine, Laboratory of Intestinal Immunity, 75015 Paris, France; Université de Paris, 75006 Paris, France.
² INSERM U1163 and Institut Imagine, Laboratory of Intestinal Immunity, 75015 Paris, France; Université de Paris, 75006 Paris, France. Electronic address: nadine.cerf-bensussan@inserm.fr.

PMID: 31117007
DOI: 10.1016/j.immuni.2019.04.013

Abstract

A link between atopic dermatitis and food allergy has long been suspected but remains elusive. In this issue, Leyva-Castillo et al. (2019) show how mechanical injury of the skin initiates a cascade of events that stimulate the expansion of mucosal mast cells and promote food anaphylaxis.

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MeSH terms

Anaphylaxis*
Dermatitis, Atopic*
Food Hypersensitivity*
Humans
Immunoglobulin E
Mast Cells

Substances

Immunoglobulin E