Relationship between the microbiome and ocular health

Ocul Surf. 2019 Jul;17(3):384-392. doi: 10.1016/j.jtos.2019.05.006. Epub 2019 May 21.


The microbiome is important to the host as a whole, both in maintenance of health and in the pathophysiology of disease. The purpose of this review is to explore the relationship between the gut, ocular microbiome, and ocular disease states. We will also discuss how the microbiome can serve as a potential target for treatment, by methods such as modulation of diet, probiotics and fecal microbiota transplantation. The information discussed in the review has been gathered using literature published from 2004 to November 2018, as indexed in PubMed.

Keywords: Dysbiosis; Gut-eye axis; Health; Microbiome; Ocular surface.

Publication types

  • Review

MeSH terms

  • Eye Diseases / microbiology
  • Eye Diseases / therapy*
  • Humans
  • Microbiota / physiology*
  • Probiotics / therapeutic use*