Hazelnut consumption improves testicular antioxidant function and semen quality in young and old male rats

Food Chem. 2019 Oct 1:294:1-8. doi: 10.1016/j.foodchem.2019.04.087. Epub 2019 Apr 25.

Abstract

The effects of hazelnut supplemented diet on the reproductive system of young and old male rats were investigated. Young male rats were grouped into young control group (YCG) and young hazelnut group (YHG). Old male rats were grouped into old control group (OCG), old hazelnut group (OHG), and old vitamin E group (OEG). While YCG and OCG were given rat feed, YHG and OHG were given rat feed supplemented with hazelnut (3 g/kg body weight). OEG was subjected to rat feed and administered vitamin E (50 mg/kg body weight). When YCG and OCG were compared, aging increased histopathological damage and decreased sperm quality. Hazelnut supplemented diet improved histopathological variables, sperm quality, seminal plasma and plasma oxidative stress, seminal plasma vitamin E, and plasma testosterone levels in both groups. The present work suggests that hazelnut supplemented diet significantly improves testicular antioxidant function and semen quality in old male rats.

Keywords: Aging; Hazelnut supplemented diet; Male reproductive system; Oxidative stress; Vitamin E.

MeSH terms

  • Animals
  • Antioxidants / chemistry
  • Corylus / chemistry*
  • Corylus / metabolism
  • Dietary Supplements*
  • Male
  • Nuts / chemistry
  • Nuts / metabolism
  • Oxidative Stress / drug effects
  • Rats
  • Rats, Sprague-Dawley
  • Semen / drug effects
  • Semen / physiology
  • Spermatozoa / drug effects
  • Spermatozoa / physiology*
  • Testis / pathology
  • Testosterone / blood
  • Vitamin E / pharmacology

Substances

  • Antioxidants
  • Vitamin E
  • Testosterone