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Review
. 2019 Apr;14(1):45-49.
doi: 10.15420/ecr.2018.31.2.

Insights for Stratification of Risk in Brugada Syndrome

Daniel García Iglesias  1   2 , José Rubín  1   2 , Diego Pérez  1   2 , César Morís  1   2 , David Calvo  1   2
Affiliations
Review

Insights for Stratification of Risk in Brugada Syndrome

Daniel García Iglesias et al. Eur Cardiol. 2019 Apr.

Abstract

Brugada syndrome (BrS) is an inherited disease with an increased risk of sudden cardiac death (SCD). However, testing identifies genetic disorders in only 20-30% of patients analysed, indicating a gap in knowledge of its genetic aetiology. Diagnosis relies on ECG, and risk stratification in BrS patients is challenging, primarily because of the complexity of the issue. As a result, clinicians fail to provide the appropriate strategy for SCD prevention for many patients. Several variables and interventions are being studied to improve diagnostics and maximise patient protection. In addition, the scientific community must increase efforts to provide patient care according to knowledge and research for improving stratification of risk. In this article, the authors summarise contemporary evidence on clinical variables and provide an overview of future directions in risk stratification and SCD prevention.

Keywords: Brugada syndrome; ECG; patient management; risk stratification; sudden cardiac death.

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Conflict of interest statement

Disclosure: The authors have no conflicts of interest to declare.

Figures

Figure 1:
Figure 1:. Example of Different Types of Brugada Pattern
Figure 2:
Figure 2:. Example of VF Induction
Figure 3:
Figure 3:. High-frequency Content Analysis Along the QRS
Figure 4:
Figure 4:. Suggested Risk Stratification for Primary Prevention in Brugada Syndrome Patients
See this image and copyright information in PMC

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